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DTSTAMP:20250808T222943Z
DESCRIPTION: \n\nT cells play an essential role in fighting infections and 
 cancer\, but inappropriate targeting of normal cells can contribute to a h
 ost of autoimmune disorders. To recognize diseased and infected cells\, T 
 cells require a diverse repertoire of antigen receptors that distinguish f
 oreign and mutated antigens from normal self-peptides. Antigen receptor di
 versity is generated during T cell development in the thymus. Within the t
 hymus\, rigorous selection processes accompany T cell differentiation to e
 nsure the functionality and self-tolerance of the unique antigen receptors
  expressed on individual T cells. Once mature T cells leave the thymus\, t
 hey encounter a battery of additional checkpoints that regulate their acti
 vation in the peripheral lymphoid organs. We will discuss the mechanisms i
 n place that regulate T cell development and function.\n\n \n\nThis semina
 r will take place both in-person and online. Details in attached poster\n
DTSTART:20230120T160000Z
DTEND:20230120T170000Z
LOCATION:Room 1034\, McIntyre Medical Building\, CA\, QC\, Montreal\, H3G 1
 Y6\, 3655 promenade Sir William Osler
SUMMARY:Physiology Seminar: Checkpoints and balances: Regulation of T cell 
 development and function
URL:/physiology/channels/event/physiology-seminar-chec
 kpoints-and-balances-regulation-t-cell-development-and-function-344515
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