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DESCRIPTION:Abstract:\n\nFerroptosis is form of cell death driven by peroxi
 dation of specific lipids. I will briefly discuss the history\, key regula
 tors\, recent emerging mechanisms\, and therapeutic applications of contro
 lling ferroptosis. I will describe how my lab recently identified an unusu
 al species of lipid that is a key driver of ferroptosis\, and how our stud
 ies linking ferroptosis to metabolism have enabled to design precision\, t
 herapeutic diets that promote ferroptosis in some cancer models.\n\n \n\nB
 io:\n\nBrent R. Stockwell\, PhD\, is the William R. Kenan Jr. Professor of
  Biological Sciences and Chair of the Department of Biological Sciences\, 
 and Professor of Chemistry in Arts & Sciences\, Columbia University\, and 
 Professor of Pathology and Cell Biology\, Vagelos College of Physicians an
 d Surgeons\, Columbia University Irving Medical Center.\n\nHis research in
 volves the discovery of small molecules that can be used to understand and
  treat cancer and neurodegeneration\, with a focus on biochemical mechanis
 ms governing cell death. In a series of papers from 2003-2012\, Dr. Stockw
 ell discovered a new form of cell death known as ferroptosis. Since then\,
  his lab has defined the major mechanisms governing ferroptosis\, its ther
 apeutic implications\, and key reagents for studying this new form of cell
  death.\n\nDr. Stockwell has received numerous awards\, including being el
 ected to the National Academy of Medicine\, receiving a Burroughs Wellcome
  Fund Career Award at the Scientific Interface\, a Beckman Young Investiga
 tor Award\, a Howard Hughes Medical Institute Early Career Scientist Award
 \, the BioAccelerate NYC Prize\, the Lenfest Distinguished Columbia Facult
 y Award\, the Great Teacher of Columbia College Award from the Society of 
 Columbia Graduates\, the Dean Peter Awn Commitment to the LGBTQ community 
 Faculty Award\, and an NCI R35 Outstanding Investigator Award. He has been
  in the top one percent of highly cited researchers the last four years an
 d was named as one of the 50 most influential life science individuals in 
 New York.\n\nProfessor Stockwell has developed a blended learning approach
  to teaching biochemistry\, performed randomized controlled trials to exam
 ine the effectiveness of teaching methods\, and introduced the use of virt
 ual reality and augmented and mixed reality into his biochemistry course. 
 He has given more than 150 seminars around the world\, trained more than 1
 00 undergraduate and graduate students\, technicians\, and postdoctoral sc
 ientists\, published >180 scientific articles\, been awarded 23 US patents
 \, and received >50 research grants for >$40 million. He founded the bioph
 armaceutical companies CombinatoRx Incorporated\, Inzen Therapeutics\, and
  ProJenX\, Inc.\, and is the author of The Quest for the Cure: The Science
  and Stories Behind the Next Generation of Medicines and is a top-ranked w
 riter on Medium.\n
DTSTART:20240402T170000Z
DTEND:20240402T183000Z
LOCATION:OM 10
SUMMARY:Chemical Society Seminar: Brent Stockwell- Ferroptosis and Metaboli
 sm: A Blueprint for Precision Diets
URL:/chemistry/channels/event/chemical-society-seminar
 -brent-stockwell-ferroptosis-and-metabolism-blueprint-precision-diets-3540
 59
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