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BEGIN:VEVENT
UID:20250824T003617EDT-6936GoKVBV@132.216.98.100
DTSTAMP:20250824T043617Z
DESCRIPTION:Abstract:\n\nNucleic acids are exquisitely adept at molecular r
 ecognition and assembly\, enabling them to direct nearly all of the proces
 ses that make life possible. These capabilities have been fine-tuned by bi
 llions of years of evolution\, and more recently\, have been harnessed in 
 the laboratory to enable the use of DNA and RNA for applications that are 
 completely unrelated to their canonical biological roles. In our lab\, we 
 seek to use DNA and RNA for applications in biosensing and biomolecular im
 aging. Specifically\, we utilize DNA aptamers as recognition elements for 
 the development of new assays for small-molecule detection and enantiopuri
 ty measurement. This has enabled applications including high-throughput mo
 nitoring of small-molecule enantiopurity for reaction optimization. We hav
 e also harnessed the specificity of protein-nucleic acid recognition for s
 elective enrichment of inosine-containing RNAs using EndoV\, enabling the 
 identification of new sites of A-to-I editing in cells. \n\nBio:\n\nJen He
 emstra received her B.S. in Chemistry from the University of California\, 
 Irvine\, in 2000. At Irvine\, she performed undergraduate research with Pr
 of. James Nowick investigating the folding of synthetic beta-sheet mimics\
 , which instilled in her a love of supramolecular chemistry. Jen then move
 d to the University of Illinois\, Urbana-Champaign\, where she completed h
 er Ph.D. with Prof. Jeffrey Moore in 2005 studying the reactivity of pyrid
 ine-functionalized phenylene ethynylene cavitands. After a brief stint in 
 industry as a medicinal chemist\, she moved to Harvard University to pursu
 e postdoctoral research with Prof. David Liu exploring mechanisms for temp
 lated nucleic acid synthesis. In 2010\, Jen began her independent career i
 n the Department of Chemistry at the University of Utah\, and was promoted
  to Associate Professor with tenure in 2016.  In 2017\, Jen and her resear
 ch group moved to the Department of Chemistry at Emory University where sh
 e was promoted to Full Professor in 2021. Research in the Heemstra lab is 
 focused on harnessing the molecular recognition and self-assembly properti
 es of nucleic acids for applications in biosensing and bioimaging.\n
DTSTART:20211116T180000Z
DTEND:20211116T193000Z
LOCATION:Zoom link: https://mcgill.zoom.us/j/81602809538?pwd=M2dBQlV2bU1CQ0
 M1dkdsVmF1R0Z0QT09
SUMMARY:Chemical Society Seminar: Jennifer Heemstra - Interrogating enzymat
 ic reactions using nucleic acid molecular recognition and assembly 
URL:/chemistry/channels/event/chemical-society-seminar
 -jennifer-heemstra-interrogating-enzymatic-reactions-using-nucleic-acid-33
 2907
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